Quality control during outgoing goods inspection

The Content Uniformity Test (CUT) is applied to test the variation of the active ingredient content of tablets and capsules within a batch and to make sure that each tablet contains the right amount intended for the active substance. 30 tablets of a batch are chosen as a representative sampling in order to perform the Content Uniformity Test. In the first stage of the test, 10 tablets are analysed individually. If the deviation proofs to be too large, the remaining 20 tablets are also analysed in a second stage.

This CUT or CUA (Content Uniformity Analysis) of pharmaceutical products is usually performed via HPLC. Therefore, the analysis used to be very time-consuming as well as resource and cost-intensive. Measurements with the new transmission Raman spectrometer TRS100 take only one second, making them faster, less expensive and more efficient.