Inprocess Raman spectrometer HyperFlux PRO during test

HyperFlux PRO Plus

In-process Raman

HyperFlux PRO Plus

The HyperFlux PRO Plus is a revolutionary in-process Raman spectrometer. Unlike other available systems, the patented High Throughput Virtual Slit Technology (HTVS™) allows 10 – 40 times the signal yield. Thus, HyperFlux PRO Plus enables more accurate chemical identification and quantification. This also applies to difficult mixtures and low concentrations. The faster measurement of dynamic reactions and lower laser power operation in hazardous environments (ATEX) speak for this new technology.

  • Patented HTVS™ technology enables super-fast real-time measurements with particularly low detection limits.
  • Compatible with numerous probes for all applications.
  • Flexible chemometrics with various software packages.
  • 21CFR p11 and IQOQ for pharmaceutical installations.
  • Up to eightfold multiplex.
  • ATEX variants available.

Areas of application

  • Real-time reaction monitoring
  • Cell culture media control
  • Monitoring of fermentation processes
  • Polymorphism / Crystallinity Monitoring
  • polymer analysis

Technical details

Measuring method High-Throughput Virtual Slit (HTVS™) Raman spectroscopy analysis
Size 467 mm x 216 mm x 137 mm (L x B x H)
Weight 9,8 kg
(excitation wavelength)
785 nm
Laser power 20 mW bis 495 mW
Spectral range 200 cm-1 bis 3300 cm-1(Raman shift von 785 nm excitation)
Sensors Immersion & Non-Contact
Fiber optic cable length 3 meter standard - different lengths available on request
Pharma-ready: 21 CFR Part 11 and IQ / OQ-Protocols
Data management Chemometric software compatible
Datatransfer USB, Ethernet (RJ45)
Ext. power supply 100 – 240 VAC, 50 – 60 Hz



Measuring probes

Various, individually modifiable measuring probes, e.g. immersion probes from Marqmetrix, contactless probes from Hellma or Hudson probe especially for measuring powders.
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OPIS35 ATEX module

Hardware module for intrinsically safe operation in EX areas up to zone 0.
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Hardware module for simultaneous operation of four of the eight channels with a HyperFlux PRO Plus.
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Calibration kit

Hg-Ar lamp and white light source for X- and Y-axis calibration.

Fibre optic maintenance kit

Fiber optic microscope, cleaning kits for fiber optic ends and input ports.

Laser Powermeter

USB-connected powermeter for determination of laser power.

Fiber optic cable

Fiber optic cable in various designs and lengths.

Flow cells

For measuring liquids in a flow-through setting, e.g. downstream biopharma.

Cuvette chamber

For measurement of samples in test cuvettes.

Do you have questions?

Are you interested in the Hyperflux PRO Plus?
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